Clustering by Plasma Lipoprotein Profile Reveals Two Distinct Subgroups with Positive Lipid Response to Fenofibrate Therapy

Fibrates lower triglycerides and raise HDL cholesterol in dyslipidemic patients, but show heterogeneous treatment response. We used k-means clustering to identify three representative NMR lipoprotein profiles for 775 subjects from the GOLDN population, and study the response to fenofibrate in corres...

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Detalles Bibliográficos
Autores principales: van Bochove, Kees, van Schalkwijk, Daniël B., Parnell, Laurence D., Lai, Chao-Qiang, Ordovás, José M., de Graaf, Albert A., van Ommen, Ben, Arnett, Donna K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373573/
https://www.ncbi.nlm.nih.gov/pubmed/22719863
http://dx.doi.org/10.1371/journal.pone.0038072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373573/
https://www.ncbi.nlm.nih.gov/pubmed/22719863
http://dx.doi.org/10.1371/journal.pone.0038072

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