Rickettsiae Induce Microvascular Hyperpermeability via Phosphorylation of VE-Cadherins: Evidence from Atomic Force Microscopy and Biochemical Studies

The most prominent pathophysiological effect of spotted fever group (SFG) rickettsial infection of microvascular endothelial cells (ECs) is an enhanced vascular permeability, promoting vasogenic cerebral edema and non-cardiogenic pulmonary edema, which are responsible for most of the morbidity and m...

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Detalles Bibliográficos
Autores principales: Gong, Bin, Ma, Liang, Liu, Yan, Gong, Qinyu, Shelite, Thomas, Bouyer, Donald, Boor, Paul J., Lee, Yong Sun, Oberhauser, Andres
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373609/
https://www.ncbi.nlm.nih.gov/pubmed/22720111
http://dx.doi.org/10.1371/journal.pntd.0001699

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373609/
https://www.ncbi.nlm.nih.gov/pubmed/22720111
http://dx.doi.org/10.1371/journal.pntd.0001699

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