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Rickettsiae Induce Microvascular Hyperpermeability via Phosphorylation of VE-Cadherins: Evidence from Atomic Force Microscopy and Biochemical Studies
The most prominent pathophysiological effect of spotted fever group (SFG) rickettsial infection of microvascular endothelial cells (ECs) is an enhanced vascular permeability, promoting vasogenic cerebral edema and non-cardiogenic pulmonary edema, which are responsible for most of the morbidity and m...
Autores principales: | Gong, Bin, Ma, Liang, Liu, Yan, Gong, Qinyu, Shelite, Thomas, Bouyer, Donald, Boor, Paul J., Lee, Yong Sun, Oberhauser, Andres |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373609/ https://www.ncbi.nlm.nih.gov/pubmed/22720111 http://dx.doi.org/10.1371/journal.pntd.0001699 |
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