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The DEAD-Box Protein Dhh1 Promotes Decapping by Slowing Ribosome Movement

Translational control and messenger RNA (mRNA) decay represent important control points in the regulation of gene expression. In yeast, the major pathway for mRNA decay is initiated by deadenylation followed by decapping and 5′–3′ exonucleolytic digestion of the mRNA. Proteins that activate decappin...

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Detalles Bibliográficos
Autores principales: Sweet, Thomas, Kovalak, Carrie, Coller, Jeff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373615/
https://www.ncbi.nlm.nih.gov/pubmed/22719226
http://dx.doi.org/10.1371/journal.pbio.1001342