An Image-Based High-Content Screening Assay for Compounds Targeting Intracellular Leishmania donovani Amastigotes in Human Macrophages

Leishmaniasis is a tropical disease threatening 350 million people from endemic regions. The available drugs for treatment are inadequate, with limitations such as serious side effects, parasite resistance or high cost. Driven by this need for new drugs, we developed a high-content, high-throughput...

Descripción completa

Detalles Bibliográficos
Autores principales: Siqueira-Neto, Jair L., Moon, Seunghyun, Jang, Jiyeon, Yang, Gyongseon, Lee, Changbok, Moon, Hong Kee, Chatelain, Eric, Genovesio, Auguste, Cechetto, Jonathan, Freitas-Junior, Lucio H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373640/
https://www.ncbi.nlm.nih.gov/pubmed/22720099
http://dx.doi.org/10.1371/journal.pntd.0001671

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373640/
https://www.ncbi.nlm.nih.gov/pubmed/22720099
http://dx.doi.org/10.1371/journal.pntd.0001671

Ejemplares similares