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Identification of Mimotopes with Diagnostic Potential for Trypanosoma brucei gambiense Variant Surface Glycoproteins Using Human Antibody Fractions

BACKGROUND: At present, screening of the population at risk for gambiense human African trypanosomiasis (HAT) is based on detection of antibodies against native variant surface glycoproteins (VSGs) of Trypanosoma brucei (T.b.) gambiense. Drawbacks of these native VSGs include culture of infective T....

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Detalles Bibliográficos
Autores principales: Van Nieuwenhove, Liesbeth, Büscher, Philippe, Balharbi, Fatima, Humbert, Michael, Dieltjens, Tessa, Guisez, Yves, Lejon, Veerle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373652/
https://www.ncbi.nlm.nih.gov/pubmed/22720103
http://dx.doi.org/10.1371/journal.pntd.0001682