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Caspase-8 regulates TNF-alpha induced epithelial necroptosis and terminal ileitis

Dysfunction of the intestinal epithelium is believed to result in excessive translocation of commensal bacteria into the bowel wall that drives chronic mucosal inflammation in Crohn's disease; an incurable inflammatory bowel disease in humans characterized by inflammation of the terminal ileum(...

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Detalles Bibliográficos
Autores principales: Günther, Claudia, Martini, Eva, Wittkopf, Nadine, Amann, Kerstin, Weigmann, Benno, Neumann, Helmut, Waldner, Maximilian, Hedrick, Stephen M., Tenzer, Stefan, Neurath, Markus F., Becker, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373730/
https://www.ncbi.nlm.nih.gov/pubmed/21921917
http://dx.doi.org/10.1038/nature10400