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Caspase-8 regulates TNF-alpha induced epithelial necroptosis and terminal ileitis
Dysfunction of the intestinal epithelium is believed to result in excessive translocation of commensal bacteria into the bowel wall that drives chronic mucosal inflammation in Crohn's disease; an incurable inflammatory bowel disease in humans characterized by inflammation of the terminal ileum(...
Autores principales: | Günther, Claudia, Martini, Eva, Wittkopf, Nadine, Amann, Kerstin, Weigmann, Benno, Neumann, Helmut, Waldner, Maximilian, Hedrick, Stephen M., Tenzer, Stefan, Neurath, Markus F., Becker, Christoph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373730/ https://www.ncbi.nlm.nih.gov/pubmed/21921917 http://dx.doi.org/10.1038/nature10400 |
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