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A reporter system for replication-competent gammaretroviruses: the inGluc-MLV-DERSE assay
While novel retroviral vectors for use in gene-therapy products are reducing the potential for formation of replication-competent retrovirus (RCR), it remains crucial to screen products for RCR for both research and clinical purposes. For clinical grade gammaretrovirus-based vectors, RCR screening i...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374051/ https://www.ncbi.nlm.nih.gov/pubmed/22402321 http://dx.doi.org/10.1038/gt.2012.18 |