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A reporter system for replication-competent gammaretroviruses: the inGluc-MLV-DERSE assay

While novel retroviral vectors for use in gene-therapy products are reducing the potential for formation of replication-competent retrovirus (RCR), it remains crucial to screen products for RCR for both research and clinical purposes. For clinical grade gammaretrovirus-based vectors, RCR screening i...

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Detalles Bibliográficos
Autores principales: Aloia, Amanda L., Duffy, Lisa, Pak, Vladimir, Lee, KyeongEun, Sanchez-Martinez, Silvia, Derse, David, Heidecker, Gisela, Cornetta, Kenneth, Rein, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374051/
https://www.ncbi.nlm.nih.gov/pubmed/22402321
http://dx.doi.org/10.1038/gt.2012.18