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Variation of the intercalating proline in artificial peptides mimicking the DNA binding and bending IHF protein

The integration host factor (IHF) is a protein which sequence specifically induces a bend of double-stranded DNA by more than 160°. Based on IHF as lead structure, a peptide mimic was introduced resembling the positively charged body of the protein by a lysine dendrimer and the minor groove recognit...

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Detalles Bibliográficos
Autores principales: Scholz, S., Liebler, E. K., Eickmann, B., Fritz, H.-J., Diederichsen, U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374092/
https://www.ncbi.nlm.nih.gov/pubmed/21922266
http://dx.doi.org/10.1007/s00726-011-1073-1