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Variation of the intercalating proline in artificial peptides mimicking the DNA binding and bending IHF protein
The integration host factor (IHF) is a protein which sequence specifically induces a bend of double-stranded DNA by more than 160°. Based on IHF as lead structure, a peptide mimic was introduced resembling the positively charged body of the protein by a lysine dendrimer and the minor groove recognit...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Vienna
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374092/ https://www.ncbi.nlm.nih.gov/pubmed/21922266 http://dx.doi.org/10.1007/s00726-011-1073-1 |