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Investigating Cell Surface Galectin-Mediated Cross-Linking on Glycoengineered Cells

[Image: see text] The galectin family of glycan-binding proteins is thought to mediate many cellular processes by oligomerizing cell surface glycoproteins and glycolipids into higher-order aggregates. This hypothesis reflects the known oligomeric states of the galectins themselves and their binding...

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Detalles Bibliográficos
Autores principales: Belardi, Brian, O’Donoghue, Geoff P., Smith, Adam W., Groves, Jay T., Bertozzi, Carolyn R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374418/
https://www.ncbi.nlm.nih.gov/pubmed/22540968
http://dx.doi.org/10.1021/ja301694s