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Plk1 regulates the kinesin-13 protein Kif2b to promote faithful chromosome segregation
Solid tumors are frequently aneuploid, and many display high rates of ongoing chromosome missegregation in a phenomenon called chromosomal instability (CIN). The most common cause of CIN is the persistence of aberrant kinetochore-microtubule (k-MT) attachments, which manifest as lagging chromosomes...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374746/ https://www.ncbi.nlm.nih.gov/pubmed/22535524 http://dx.doi.org/10.1091/mbc.E11-12-1013 |