Activation of EGFR/ERBB2 via Pathways Involving ERK1/2, P38 MAPK, AKT and FOXO Enhances Recovery of Diabetic Hearts from Ischemia-Reperfusion Injury

This study characterized the effects of diabetes and/or ischemia on epidermal growth factor receptor, EGFR, and/or erbB2 signaling pathways on cardiac function. Isolated heart perfusion model of global ischemia was used to study the effect of chronic inhibition or acute activation of EGFR/erbB2 sign...

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Detalles Bibliográficos
Autores principales: Akhtar, Saghir, Yousif, Mariam H. M., Chandrasekhar, Bindu, Benter, Ibrahim F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374768/
https://www.ncbi.nlm.nih.gov/pubmed/22720029
http://dx.doi.org/10.1371/journal.pone.0039066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374768/
https://www.ncbi.nlm.nih.gov/pubmed/22720029
http://dx.doi.org/10.1371/journal.pone.0039066

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