Vanin-1 Pantetheinase Drives Smooth Muscle Cell Activation in Post-Arterial Injury Neointimal Hyperplasia

The pantetheinase vanin-1 generates cysteamine, which inhibits reduced glutathione (GSH) synthesis. Vanin-1 promotes inflammation and tissue injury partly by inducing oxidative stress, and partly by peroxisome proliferator-activated receptor gamma (PPARγ) expression. Vascular smooth muscle cells (SM...

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Detalles Bibliográficos
Autores principales: Dammanahalli, K. Jagadeesha, Stevens, Stephanie, Terkeltaub, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374784/
https://www.ncbi.nlm.nih.gov/pubmed/22720042
http://dx.doi.org/10.1371/journal.pone.0039106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374784/
https://www.ncbi.nlm.nih.gov/pubmed/22720042
http://dx.doi.org/10.1371/journal.pone.0039106

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