Broader Neutralizing Antibodies against H5N1 Viruses Using Prime-Boost Immunization of Hyperglycosylated Hemagglutinin DNA and Virus-Like Particles

BACKGROUND: Highly pathogenic avian influenza (HPAI) H5N1 viruses and their transmission capability from birds to humans have raised global concerns about a potential human pandemic. The inherent nature of antigenic changes in influenza viruses has not been sufficiently taken into account in immunog...

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Detalles Bibliográficos
Autores principales: Lin, Shih-Chang, Lin, Yu-Fen, Chong, Pele, Wu, Suh-Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374787/
https://www.ncbi.nlm.nih.gov/pubmed/22720032
http://dx.doi.org/10.1371/journal.pone.0039075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374787/
https://www.ncbi.nlm.nih.gov/pubmed/22720032
http://dx.doi.org/10.1371/journal.pone.0039075

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