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Radioiodinated Phenylalkyl Malonic Acid Derivatives as pH-Sensitive SPECT Tracers

INTRODUCTION: In vivo pH imaging has been a field of interest for molecular imaging for many years. This is especially important for determining tumor acidity, an important driving force of tumor invasion and metastasis formation, but also in the process of apoptosis. METHODS: 2-(4-[(123)I]iodophene...

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Detalles Bibliográficos
Autores principales: Bauwens, Matthias, De Saint-Hubert, Marijke, Cleynhens, Jan, Brams, Laura, Devos, Ellen, Mottaghy, Felix M., Verbruggen, Alfons
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374791/
https://www.ncbi.nlm.nih.gov/pubmed/22719886
http://dx.doi.org/10.1371/journal.pone.0038428