Cargando…

Notch-RBP-J-Independent Marginal Zone B Cell Development in IgH Transgenic Mice with V(H) Derived from a Natural Polyreactive Antibody

Both the B cell antigen receptor (BCR) signaling and Notch signaling pathway play important roles in marginal zone (MZ) B cell development; however, if and how these two signaling pathways engage in crosstalk with each other remain unclear. In the present study, IgH transgenic mice (TgV(H)3B4) were...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Zhuo, Zhou, Lanhua, Yang, Xinwei, Wang, Yaochun, Zhang, Ping, Hou, Lihong, Hu, Xinbin, Xing, Ying, Liu, Yufeng, Li, Wei, Han, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374804/
https://www.ncbi.nlm.nih.gov/pubmed/22719978
http://dx.doi.org/10.1371/journal.pone.0038894