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The Adenomatous Polyposis Coli Protein Contributes to Normal Compaction of Mitotic Chromatin
The tumour suppressor Adenomatous Polyposis Coli (APC) is required for proper mitosis; however, the exact role of APC in mitosis is not understood. Using demembranated sperm chromatin exposed to meiotic Xenopus egg extract and HeLa cells expressing fluorescently labelled histones, we established tha...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374815/ https://www.ncbi.nlm.nih.gov/pubmed/22719865 http://dx.doi.org/10.1371/journal.pone.0038102 |