The Adenomatous Polyposis Coli Protein Contributes to Normal Compaction of Mitotic Chromatin

The tumour suppressor Adenomatous Polyposis Coli (APC) is required for proper mitosis; however, the exact role of APC in mitosis is not understood. Using demembranated sperm chromatin exposed to meiotic Xenopus egg extract and HeLa cells expressing fluorescently labelled histones, we established tha...

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Detalles Bibliográficos
Autores principales: Dikovskaya, Dina, Khoudoli, Guennadi, Newton, Ian P., Chadha, Gaganmeet S., Klotz, Daniel, Visvanathan, Ashwat, Lamond, Angus, Swedlow, Jason R., Näthke, Inke S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374815/
https://www.ncbi.nlm.nih.gov/pubmed/22719865
http://dx.doi.org/10.1371/journal.pone.0038102

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