The Structure of the Oligomerization Domain of Lsr2 from Mycobacterium tuberculosis Reveals a Mechanism for Chromosome Organization and Protection

Lsr2 is a small DNA-binding protein present in mycobacteria and related actinobacteria that regulates gene expression and influences the organization of bacterial chromatin. Lsr2 is a dimer that binds to AT-rich regions of chromosomal DNA and physically protects DNA from damage by reactive oxygen in...

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Detalles Bibliográficos
Autores principales: Summers, Emma L., Meindl, Kathrin, Usón, Isabel, Mitra, Alok K., Radjainia, Mazdak, Colangeli, Roberto, Alland, David, Arcus, Vickery L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374832/
https://www.ncbi.nlm.nih.gov/pubmed/22719899
http://dx.doi.org/10.1371/journal.pone.0038542

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374832/
https://www.ncbi.nlm.nih.gov/pubmed/22719899
http://dx.doi.org/10.1371/journal.pone.0038542

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