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The Structure of the Oligomerization Domain of Lsr2 from Mycobacterium tuberculosis Reveals a Mechanism for Chromosome Organization and Protection
Lsr2 is a small DNA-binding protein present in mycobacteria and related actinobacteria that regulates gene expression and influences the organization of bacterial chromatin. Lsr2 is a dimer that binds to AT-rich regions of chromosomal DNA and physically protects DNA from damage by reactive oxygen in...
Autores principales: | Summers, Emma L., Meindl, Kathrin, Usón, Isabel, Mitra, Alok K., Radjainia, Mazdak, Colangeli, Roberto, Alland, David, Arcus, Vickery L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374832/ https://www.ncbi.nlm.nih.gov/pubmed/22719899 http://dx.doi.org/10.1371/journal.pone.0038542 |
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