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Forced Abstinence from Cocaine Self-Administration is Associated with DNA Methylation Changes in Myelin Genes in the Corpus Callosum: a Preliminary Study

Background: Human cocaine abuse is associated with alterations in white matter integrity revealed upon brain imaging, an observation that is recapitulated in an animal model of continuous cocaine exposure. The mechanism through which cocaine may affect white matter is unknown and the present study t...

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Detalles Bibliográficos
Autores principales: Nielsen, David A., Huang, Wen, Hamon, Sara C., Maili, Lorena, Witkin, Brian M., Fox, Robert G., Cunningham, Kathryn A., Moeller, F. Gerard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374938/
https://www.ncbi.nlm.nih.gov/pubmed/22712019
http://dx.doi.org/10.3389/fpsyt.2012.00060