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Forced Abstinence from Cocaine Self-Administration is Associated with DNA Methylation Changes in Myelin Genes in the Corpus Callosum: a Preliminary Study
Background: Human cocaine abuse is associated with alterations in white matter integrity revealed upon brain imaging, an observation that is recapitulated in an animal model of continuous cocaine exposure. The mechanism through which cocaine may affect white matter is unknown and the present study t...
Autores principales: | Nielsen, David A., Huang, Wen, Hamon, Sara C., Maili, Lorena, Witkin, Brian M., Fox, Robert G., Cunningham, Kathryn A., Moeller, F. Gerard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374938/ https://www.ncbi.nlm.nih.gov/pubmed/22712019 http://dx.doi.org/10.3389/fpsyt.2012.00060 |
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