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Oxidative Stress: A Pathogenic Mechanism for Niemann-Pick Type C Disease

Niemann-Pick type C (NPC) disease is a neurovisceral atypical lipid storage disorder involving the accumulation of cholesterol and other lipids in the late endocytic pathway. The pathogenic mechanism that links the accumulation of intracellular cholesterol with cell death in NPC disease in both the...

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Detalles Bibliográficos
Autores principales: Vázquez, Mary Carmen, Balboa, Elisa, Alvarez, Alejandra R., Zanlungo, Silvana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374944/
https://www.ncbi.nlm.nih.gov/pubmed/22720116
http://dx.doi.org/10.1155/2012/205713