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The TRPV5/6 calcium channels contain multiple calmodulin binding sites with differential binding properties

The epithelial Ca(2+) channels TRPV5/6 (transient receptor potential vanilloid 5/6) are thoroughly regulated in order to fine-tune the amount of Ca(2+) reabsorption. Calmodulin has been shown to be involved into calcium-dependent inactivation of TRPV5/6 channels by binding directly to the distal C-t...

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Detalles Bibliográficos
Autores principales: Kovalevskaya, Nadezda V., Bokhovchuk, Fedir M., Vuister, Geerten W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375010/
https://www.ncbi.nlm.nih.gov/pubmed/22354706
http://dx.doi.org/10.1007/s10969-012-9128-4