Characterization and Solubilization of Pyrrole–Imidazole Polyamide Aggregates

[Image: see text] To optimize the biological activity of pyrrole–imidazole polyamide DNA-binding molecules, we characterized the aggregation propensity of these compounds through dynamic light scattering and fractional solubility analysis. Nearly all studied polyamides were found to form measurable...

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Detalles Bibliográficos
Autores principales: Hargrove, Amanda E., Raskatov, Jevgenij A., Meier, Jordan L., Montgomery, David C., Dervan, Peter B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375050/
https://www.ncbi.nlm.nih.gov/pubmed/22607187
http://dx.doi.org/10.1021/jm300380a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375050/
https://www.ncbi.nlm.nih.gov/pubmed/22607187
http://dx.doi.org/10.1021/jm300380a

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