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Association of Base Excision Repair Gene Polymorphisms with ESRD Risk in a Chinese Population

The base excision repair (BER) pathway, containing OGG1, MTH1 and MUTYH, is a major protector from oxidative DNA damage in humans, while 8-oxoguanine (8-OHdG), an index of DNA oxidation, is increased in maintenance hemodialysis (HD) patients. Four polymorphisms of BER genes, OGG1 c.977C > G (rs10...

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Detalles Bibliográficos
Autores principales: Cai, Zhenming, Chen, Huimei, Tao, Jing, Guo, Wenwen, Liu, Xiufang, Zheng, Bixia, Sun, Wei, Wang, Yaping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375099/
https://www.ncbi.nlm.nih.gov/pubmed/22720119
http://dx.doi.org/10.1155/2012/928421