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Lessons from Tau-Deficient Mice

Both Alzheimer's disease (AD) and frontotemporal dementia (FTD) are characterized by the deposition of hyperphosphorylated forms of the microtubule-associated protein tau in neurons and/or glia. This unifying pathology led to the umbrella term “tauopathies” for these conditions, also emphasizin...

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Detalles Bibliográficos
Autores principales: Ke, Yazi D., Suchowerska, Alexandra K., van der Hoven, Julia, De Silva, Dineeka M., Wu, Christopher W., van Eersel, Janet, Ittner, Arne, Ittner, Lars M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375147/
https://www.ncbi.nlm.nih.gov/pubmed/22720190
http://dx.doi.org/10.1155/2012/873270