Na(+)/H(+)-exchanger-1 inhibition counteracts diabetic cataract formation and retinal oxidative-nitrative stress and apoptosis

The Na(+)-H(+)-exchanger-1 (NHE-1) controls intracellular pH and glycolytic enzyme activities, and its expression and activity are increased by diabetes and high glucose. NHE-1-dependent upregulation of the upper part of glycolysis, under conditions of inhibition (lens) or insufficient activation (r...

Descripción completa

Detalles Bibliográficos
Autores principales: LUPACHYK, SERGEY, STAVNIICHUK, ROMAN, KOMISSARENKO, JULIA I., DREL, VIKTOR R., OBROSOV, ALEXANDER A., EL-REMESSY, AZZA B., PACHER, PAL, OBROSOVA, IRINA G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375174/
https://www.ncbi.nlm.nih.gov/pubmed/22407349
http://dx.doi.org/10.3892/ijmm.2012.933

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375174/
https://www.ncbi.nlm.nih.gov/pubmed/22407349
http://dx.doi.org/10.3892/ijmm.2012.933

Ejemplares similares