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Sphingosine Kinase-1-Dependent and -Independent Inhibitory Effects of Zanthoxyli Fructus to Attenuate the Activation of Mucosal Mast Cells and Ameliorate Food Allergies in Mice

Food allergy (FA) is relatively a common disease in infants, but effective drug therapies are not yet available. Notably, mucosal mast cells, but not connective-tissue mast cells, play important roles in food allergic reactions via the release of inflammatory mediators. Therefore, we screened medici...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoyu, Kageyama-Yahara, Natsuko, Hayashi, Shusaku, Yamamoto, Takeshi, Kadowaki, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375181/
https://www.ncbi.nlm.nih.gov/pubmed/22719791
http://dx.doi.org/10.1155/2012/862743