Diosgenin Induces Apoptosis in HepG2 Cells through Generation of Reactive Oxygen Species and Mitochondrial Pathway

Diosgenin, a naturally occurring steroid saponin found abundantly in legumes and yams, is a precursor of various synthetic steroidal drugs. Diosgenin is studied for the mechanism of its action in apoptotic pathway in human hepatocellular carcinoma cells. Based on DAPI staining, diosgenin-treated cel...

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Detalles Bibliográficos
Autores principales: Kim, Dae Sung, Jeon, Byoung Kook, Lee, Young Eun, Woo, Won Hong, Mun, Yeun Ja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375183/
https://www.ncbi.nlm.nih.gov/pubmed/22719792
http://dx.doi.org/10.1155/2012/981675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375183/
https://www.ncbi.nlm.nih.gov/pubmed/22719792
http://dx.doi.org/10.1155/2012/981675

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