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Diosgenin Induces Apoptosis in HepG2 Cells through Generation of Reactive Oxygen Species and Mitochondrial Pathway

Diosgenin, a naturally occurring steroid saponin found abundantly in legumes and yams, is a precursor of various synthetic steroidal drugs. Diosgenin is studied for the mechanism of its action in apoptotic pathway in human hepatocellular carcinoma cells. Based on DAPI staining, diosgenin-treated cel...

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Detalles Bibliográficos
Autores principales:	Kim, Dae Sung, Jeon, Byoung Kook, Lee, Young Eun, Woo, Won Hong, Mun, Yeun Ja
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375183/ https://www.ncbi.nlm.nih.gov/pubmed/22719792 http://dx.doi.org/10.1155/2012/981675

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