Bisquinolinium compounds induce quadruplex-specific transcriptome changes in HeLa S3 cell lines

BACKGROUND: Guanosine rich sequences capable of forming G-quadruplex (G4) motifs are enriched near the gene transcription start site (TSS) in the human genome. When probed at the single gene level, G-quadruplex motifs residing in promoter regions show substantial effects on gene transcription. Moreo...

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Detalles Bibliográficos
Autores principales: Halder, Rashi, Riou, Jean-Francois, Teulade-Fichou, Marie-Paule, Frickey, Tancred, Hartig, Jörg S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375199/
https://www.ncbi.nlm.nih.gov/pubmed/22414013
http://dx.doi.org/10.1186/1756-0500-5-138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375199/
https://www.ncbi.nlm.nih.gov/pubmed/22414013
http://dx.doi.org/10.1186/1756-0500-5-138

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