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Bisquinolinium compounds induce quadruplex-specific transcriptome changes in HeLa S3 cell lines
BACKGROUND: Guanosine rich sequences capable of forming G-quadruplex (G4) motifs are enriched near the gene transcription start site (TSS) in the human genome. When probed at the single gene level, G-quadruplex motifs residing in promoter regions show substantial effects on gene transcription. Moreo...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375199/ https://www.ncbi.nlm.nih.gov/pubmed/22414013 http://dx.doi.org/10.1186/1756-0500-5-138 |