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Caspase Inhibitors of the P35 Family Are More Active When Purified from Yeast than Bacteria

Many insect viruses express caspase inhibitors of the P35 superfamily, which prevent defensive host apoptosis to enable viral propagation. The prototypical P35 family member, AcP35 from Autographa californica M nucleopolyhedrovirus, has been extensively studied. Bacterially purified AcP35 has been p...

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Detalles Bibliográficos
Autores principales: Brand, Ingo L., Civciristov, Srgjan, Taylor, Nicole L., Talbo, Gert H., Pantaki-Eimany, Delara, Levina, Vita, Clem, Rollie J., Perugini, Matthew A., Kvansakul, Marc, Hawkins, Christine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375223/
https://www.ncbi.nlm.nih.gov/pubmed/22720082
http://dx.doi.org/10.1371/journal.pone.0039248