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The Histone Demethylase Jhdm1a Regulates Hepatic Gluconeogenesis
Hepatic gluconeogenesis is required for maintaining blood glucose homeostasis; yet, in diabetes mellitus, this process is unrestrained and is a major contributor to fasting hyperglycemia. To date, the impacts of chromatin modifying enzymes and chromatin landscape on gluconeogenesis are poorly unders...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375226/ https://www.ncbi.nlm.nih.gov/pubmed/22719268 http://dx.doi.org/10.1371/journal.pgen.1002761 |