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The Histone Demethylase Jhdm1a Regulates Hepatic Gluconeogenesis

Hepatic gluconeogenesis is required for maintaining blood glucose homeostasis; yet, in diabetes mellitus, this process is unrestrained and is a major contributor to fasting hyperglycemia. To date, the impacts of chromatin modifying enzymes and chromatin landscape on gluconeogenesis are poorly unders...

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Detalles Bibliográficos
Autores principales: Pan, Dongning, Mao, Chunxiao, Zou, Tie, Yao, Annie Y., Cooper, Marcus P., Boyartchuk, Victor, Wang, Yong-Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375226/
https://www.ncbi.nlm.nih.gov/pubmed/22719268
http://dx.doi.org/10.1371/journal.pgen.1002761