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Specific Marking of hESCs-Derived Hematopoietic Lineage by WAS-Promoter Driven Lentiviral Vectors

Genetic manipulation of human embryonic stem cells (hESCs) is instrumental for tracing lineage commitment and to studying human development. Here we used hematopoietic-specific Wiskott-Aldrich syndrome gene (WAS)-promoter driven lentiviral vectors (LVs) to achieve highly specific gene expression in...

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Detalles Bibliográficos
Autores principales: Muñoz, Pilar, Toscano, Miguel G., Real, Pedro J., Benabdellah, Karim, Cobo, Marién, Bueno, Clara, Ramos-Mejía, Verónica, Menendez, Pablo, Anderson, Per, Martín, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375235/
https://www.ncbi.nlm.nih.gov/pubmed/22720040
http://dx.doi.org/10.1371/journal.pone.0039091