Cargando…
Protective Coupling of Mitochondrial Function and Protein Synthesis via the eIF2α Kinase GCN-2
Cells respond to defects in mitochondrial function by activating signaling pathways that restore homeostasis. The mitochondrial peptide exporter HAF-1 and the bZip transcription factor ATFS-1 represent one stress response pathway that regulates the transcription of mitochondrial chaperone genes duri...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375257/ https://www.ncbi.nlm.nih.gov/pubmed/22719267 http://dx.doi.org/10.1371/journal.pgen.1002760 |