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Protective Coupling of Mitochondrial Function and Protein Synthesis via the eIF2α Kinase GCN-2

Cells respond to defects in mitochondrial function by activating signaling pathways that restore homeostasis. The mitochondrial peptide exporter HAF-1 and the bZip transcription factor ATFS-1 represent one stress response pathway that regulates the transcription of mitochondrial chaperone genes duri...

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Detalles Bibliográficos
Autores principales:	Baker, Brooke M., Nargund, Amrita M., Sun, Tiffany, Haynes, Cole M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375257/ https://www.ncbi.nlm.nih.gov/pubmed/22719267 http://dx.doi.org/10.1371/journal.pgen.1002760

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