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Deficient Dopamine D(2) Receptor Function Causes Renal Inflammation Independently of High Blood Pressure

Renal dopamine receptors participate in the regulation of blood pressure. Genetic factors, including polymorphisms of the dopamine D(2) receptor gene (DRD2) are associated with essential hypertension, but the mechanisms of their contribution are incompletely understood. Mice lacking Drd2 (D(2)−/−) h...

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Detalles Bibliográficos
Autores principales: Zhang, Yanrong, Cuevas, Santiago, Asico, Laureano D., Escano, Crisanto, Yang, Yu, Pascua, Annabelle M., Wang, Xiaoyan, Jones, John E., Grandy, David, Eisner, Gilbert, Jose, Pedro A., Armando, Ines
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375266/
https://www.ncbi.nlm.nih.gov/pubmed/22719934
http://dx.doi.org/10.1371/journal.pone.0038745