Glucocorticoid Receptor and Sequential P53 Activation by Dexamethasone Mediates Apoptosis and Cell Cycle Arrest of Osteoblastic MC3T3-E1 Cells

Glucocorticoids play a pivotal role in the proliferation of osteoblasts, but the underlying mechanism has not been successfully elucidated. In this report, we have investigated the molecular mechanism which elucidates the inhibitory effects of dexamethasone on murine osteoblastic MC3T3-E1 cells. It...

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Detalles Bibliográficos
Autores principales: Li, Hui, Qian, Wenwei, Weng, Xisheng, Wu, Zhihong, Li, Huihua, Zhuang, Qianyu, Feng, Bin, Bian, Yanyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375272/
https://www.ncbi.nlm.nih.gov/pubmed/22719835
http://dx.doi.org/10.1371/journal.pone.0037030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375272/
https://www.ncbi.nlm.nih.gov/pubmed/22719835
http://dx.doi.org/10.1371/journal.pone.0037030

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