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The Salmonella Deubiquitinase SseL Inhibits Selective Autophagy of Cytosolic Aggregates

Cell stress and infection promote the formation of ubiquitinated aggregates in both non-immune and immune cells. These structures are recognised by the autophagy receptor p62/sequestosome 1 and are substrates for selective autophagy. The intracellular growth of Salmonella enterica occurs in a membra...

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Detalles Bibliográficos
Autores principales: Mesquita, Francisco S., Thomas, Mair, Sachse, Martin, Santos, António J. M., Figueira, Rita, Holden, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375275/
https://www.ncbi.nlm.nih.gov/pubmed/22719249
http://dx.doi.org/10.1371/journal.ppat.1002743