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HIV-Specific Antibodies Capable of ADCC Are Common in Breastmilk and Are Associated with Reduced Risk of Transmission in Women with High Viral Loads

There are limited data describing the functional characteristics of HIV-1 specific antibodies in breast milk (BM) and their role in breastfeeding transmission. The ability of BM antibodies to bind HIV-1 envelope, neutralize heterologous and autologous viruses and direct antibody-dependent cell cytot...

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Detalles Bibliográficos
Autores principales: Mabuka, Jennifer, Nduati, Ruth, Odem-Davis, Katherine, Peterson, Dylan, Overbaugh, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375288/
https://www.ncbi.nlm.nih.gov/pubmed/22719248
http://dx.doi.org/10.1371/journal.ppat.1002739