Improving Disease Gene Prioritization by Comparing the Semantic Similarity of Phenotypes in Mice with Those of Human Diseases

Despite considerable progress in understanding the molecular origins of hereditary human diseases, the molecular basis of several thousand genetic diseases still remains unknown. High-throughput phenotype studies are underway to systematically assess the phenotype outcome of targeted mutations in mo...

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Detalles Bibliográficos
Autores principales: Oellrich, Anika, Hoehndorf, Robert, Gkoutos, Georgios V., Rebholz-Schuhmann, Dietrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375301/
https://www.ncbi.nlm.nih.gov/pubmed/22719993
http://dx.doi.org/10.1371/journal.pone.0038937

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375301/
https://www.ncbi.nlm.nih.gov/pubmed/22719993
http://dx.doi.org/10.1371/journal.pone.0038937

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