Inhibition of Soluble Epoxide Hydrolase Attenuates High-Fat-Diet–Induced Hepatic Steatosis by Reduced Systemic Inflammatory Status in Mice

Non-alcoholic fatty liver disease is associated with obesity and considered an inflammatory disease. Soluble epoxide hydrolase (sEH) is a major enzyme hydrolyzing epoxyeicosatrienoic acids and attenuates their cardiovascular protective and anti-inflammatory effects. We examined whether sEH inhibitio...

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Detalles Bibliográficos
Autores principales: Liu, Yan, Dang, Huaixin, Li, Dan, Pang, Wei, Hammock, Bruce D., Zhu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375303/
https://www.ncbi.nlm.nih.gov/pubmed/22720061
http://dx.doi.org/10.1371/journal.pone.0039165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375303/
https://www.ncbi.nlm.nih.gov/pubmed/22720061
http://dx.doi.org/10.1371/journal.pone.0039165

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