Cargando…

Inhibition of Soluble Epoxide Hydrolase Attenuates High-Fat-Diet–Induced Hepatic Steatosis by Reduced Systemic Inflammatory Status in Mice

Non-alcoholic fatty liver disease is associated with obesity and considered an inflammatory disease. Soluble epoxide hydrolase (sEH) is a major enzyme hydrolyzing epoxyeicosatrienoic acids and attenuates their cardiovascular protective and anti-inflammatory effects. We examined whether sEH inhibitio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Yan, Dang, Huaixin, Li, Dan, Pang, Wei, Hammock, Bruce D., Zhu, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375303/ https://www.ncbi.nlm.nih.gov/pubmed/22720061 http://dx.doi.org/10.1371/journal.pone.0039165

Ejemplares similares

Soluble Epoxide Hydrolase Deletion Limits High-Fat Diet-Induced Inflammation
por: Wagner, Karen M., et al.
Publicado: (2021)

Soluble Epoxide Hydrolase in Atherosclerosis
por: Wang, Yi-Xin Jim, et al.
Publicado: (2010)

Effects of Individual Circulating FFAs on Plasma and Hepatic FFA Epoxides, Diols, and Epoxide-Diol Ratios as Indices of Soluble Epoxide Hydrolase Activity
por: Oh, Young Taek, et al.
Publicado: (2023)

Pharmacological Inhibition of Soluble Epoxide Hydrolase Ameliorates Diet-Induced Metabolic Syndrome in Rats
por: Iyer, Abishek, et al.
Publicado: (2012)

Soluble epoxide hydrolase inhibition alleviates chemotherapy induced neuropathic pain
por: Takeshita, Ashley A., et al.
Publicado: (2023)

Soluble Epoxide Hydrolase Hepatic Deficiency Ameliorates Alcohol-Associated Liver Disease
por: Mello, Aline, et al.
Publicado: (2020)

Design and Potency of Dual Soluble Epoxide Hydrolase/Fatty Acid Amide Hydrolase Inhibitors
por: Kodani, Sean D., et al.
Publicado: (2018)

Effects of Soluble Epoxide Hydrolase Deficiency on Acute Pancreatitis in Mice
por: Bettaieb, Ahmed, et al.
Publicado: (2014)

Opposite Effects of Gene Deficiency and Pharmacological Inhibition of Soluble Epoxide Hydrolase on Cardiac Fibrosis
por: Li, Lijuan, et al.
Publicado: (2014)

Inhibition of the Soluble Epoxide Hydrolase as an Analgesic Strategy: A Review of Preclinical Evidence
por: Wang, Yuxin, et al.
Publicado: (2021)

Evaluation of fish models of soluble epoxide hydrolase inhibition.
por: Newman, J W, et al.
Publicado: (2001)

Pharmaceutical Effects of Inhibiting the Soluble Epoxide Hydrolase in Canine Osteoarthritis
por: McReynolds, Cindy B., et al.
Publicado: (2019)

Inhibition of soluble epoxide hydrolase increases coronary perfusion in mice
por: Qin, Jun, et al.
Publicado: (2015)

Dysregulation of Soluble Epoxide Hydrolase and Lipidomic Profiles in Anorexia Nervosa
por: Shih, Pei-an Betty, et al.
Publicado: (2015)

Occurrence of urea-based soluble epoxide hydrolase inhibitors from the plants in the order Brassicales
por: Kitamura, Seiya, et al.
Publicado: (2017)

Selection of Potent Inhibitors of Soluble Epoxide Hydrolase for Usage in Veterinary Medicine
por: Shihadih, Diyala S., et al.
Publicado: (2020)

Soluble Epoxide Hydrolase Is Associated with Postprandial Anxiety Decrease in Healthy Adult Women
por: Nguyen, Nhien, et al.
Publicado: (2022)

Soluble epoxide hydrolase inhibition decreases reperfusion injury after focal cerebral ischemia
por: Tu, Ranran, et al.
Publicado: (2018)

Role of the soluble epoxide hydrolase in the hair follicle stem cell homeostasis and hair growth
por: Naeem, Zumer, et al.
Publicado: (2022)

Soluble Epoxide Hydrolase Contributes to Cell Senescence and ER Stress in Aging Mice Colon
por: Wang, Weicang, et al.
Publicado: (2023)

Soluble Epoxide Hydrolase Inhibition by t-TUCB Promotes Brown Adipogenesis and Reduces Serum Triglycerides in Diet-Induced Obesity
por: Overby, Haley, et al.
Publicado: (2020)

Soluble Epoxide Hydrolase and Diabetes Complications
por: Anita, Natasha Z., et al.
Publicado: (2022)

Relative Importance of Soluble and Microsomal Epoxide Hydrolases for the Hydrolysis of Epoxy-Fatty Acids in Human Tissues
por: Morisseau, Christophe, et al.
Publicado: (2021)

2-(Piperidin-4-yl)acetamides as Potent Inhibitors of Soluble Epoxide Hydrolase with Anti-Inflammatory Activity
por: Martín-López, Juan, et al.
Publicado: (2021)

Inhibition of the Soluble Epoxide Hydrolase Promotes Albuminuria in Mice with Progressive Renal Disease
por: Jung, Oliver, et al.
Publicado: (2010)

Lack of rewarding effects of a soluble epoxide hydrolase inhibitor TPPU in mice: Comparison with morphine
por: Wan, Xiayun, et al.
Publicado: (2020)

Aflatoxin B(1) Increases Soluble Epoxide Hydrolase in the Brain and Induces Neuroinflammation and Dopaminergic Neurotoxicity
por: Wang, Weicang, et al.
Publicado: (2023)

Author Correction: Soluble epoxide hydrolase inhibition decreases reperfusion injury after focal cerebral ischemia
por: Tu, Ranran, et al.
Publicado: (2021)

Structure-guided discovery of potent and oral soluble epoxide hydrolase inhibitors for the treatment of neuropathic pain
por: Du, Fangyu, et al.
Publicado: (2022)

Quantification of soluble epoxide hydrolase inhibitors in experimental and clinical samples using the nanobody-based ELISA
por: Yang, Huiyi, et al.
Publicado: (2023)

Effects of chronic secondhand smoke exposure on cardiovascular regulation and the role of soluble epoxide hydrolase in mice
por: Pan, Shiyue, et al.
Publicado: (2023)

Bioactivation of leukotoxins to their toxic diols by epoxide hydrolase
por: Moghaddam, Mehran F., et al.
Publicado: (1997)

Deletion of soluble epoxide hydrolase attenuates mice Hyperoxic acute lung injury
por: Liu, Li-Ping, et al.
Publicado: (2018)

Inhibition of Soluble Epoxide Hydrolase Attenuates Bosutinib-Induced Blood Pressure Elevation
por: Cui, Zhen, et al.
Publicado: (2021)

Inhibition of Soluble Epoxide Hydrolase for Renal Health
por: Liu, Jun-Yan
Publicado: (2019)

Soluble Epoxide Hydrolase and Brain Cholesterol Metabolism
por: Domingues, Michelle Flores, et al.
Publicado: (2020)

Soluble epoxide hydrolase inhibitor, TPPU, increases regulatory T cells pathway in an arthritis model
por: Trindade‐da‐Silva, Carlos A., et al.
Publicado: (2020)

Differential Effects of 17,18-EEQ and 19,20-EDP Combined with Soluble Epoxide Hydrolase Inhibitor t-TUCB on Diet-Induced Obesity in Mice
por: Yang, Yang, et al.
Publicado: (2021)

Impact of diabetes on male sexual function in streptozotocin-induced diabetic rats: Protective role of soluble epoxide hydrolase inhibitor
por: Minaz, Nathani, et al.
Publicado: (2019)

Soluble Epoxide Hydrolase Inhibition and Epoxyeicosatrienoic Acid Treatment Improve Vascularization of Engineered Skin Substitutes
por: Supp, Dorothy M., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_rnpp7g9cghmo9c2u66b7s9sqno