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Evidence for Induction of Integron-Based Antibiotic Resistance by the SOS Response in a Clinical Setting

Bacterial resistance to β-lactams may rely on acquired β-lactamases encoded by class 1 integron-borne genes. Rearrangement of integron cassette arrays is mediated by the integrase IntI1. It has been previously established that integrase expression can be activated by the SOS response in vitro, leadi...

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Detalles Bibliográficos
Autores principales: Hocquet, Didier, Llanes, Catherine, Thouverez, Michelle, Kulasekara, Hemantha D., Bertrand, Xavier, Plésiat, Patrick, Mazel, Didier, Miller, Samuel I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375312/
https://www.ncbi.nlm.nih.gov/pubmed/22719259
http://dx.doi.org/10.1371/journal.ppat.1002778