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Conditional Stat1 Ablation Reveals the Importance of Interferon Signaling for Immunity to Listeria monocytogenes Infection

Signal transducer and activator of transcription 1 (Stat1) is a key player in responses to interferons (IFN). Mutations of Stat1 cause severe immune deficiencies in humans and mice. Here we investigate the importance of Stat1 signaling for the innate and secondary immune response to the intracellula...

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Detalles Bibliográficos
Autores principales: Kernbauer, Elisabeth, Maier, Verena, Stoiber, Dagmar, Strobl, Birgit, Schneckenleithner, Christine, Sexl, Veronika, Reichart, Ursula, Reizis, Boris, Kalinke, Ulrich, Jamieson, Amanda, Müller, Mathias, Decker, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375314/
https://www.ncbi.nlm.nih.gov/pubmed/22719255
http://dx.doi.org/10.1371/journal.ppat.1002763