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A signal processing approach for enriched region detection in RNA polymerase II ChIP-seq data

BACKGROUND: RNA polymerase II (PolII) is essential in gene transcription and ChIP-seq experiments have been used to study PolII binding patterns over the entire genome. However, since PolII enriched regions in the genome can be very long, existing peak finding algorithms for ChIP-seq data are not ad...

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Detalles Bibliográficos
Autores principales: Han, Zhi, Tian, Lu, Pécot, Thierry, Huang, Tim, Machiraju, Raghu, Huang, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375632/
https://www.ncbi.nlm.nih.gov/pubmed/22536865
http://dx.doi.org/10.1186/1471-2105-13-S2-S2