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The post-mitotic state in neurons correlates with a stable nuclear higher-order structure
Neurons become terminally differentiated (TD) post-mitotic cells very early during development yet they may remain alive and functional for decades. TD neurons preserve the molecular machinery necessary for DNA synthesis that may be reactivated by different stimuli but they never complete a successf...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Landes Bioscience
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376047/ https://www.ncbi.nlm.nih.gov/pubmed/22808316 http://dx.doi.org/10.4161/cib.18761 |