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The post-mitotic state in neurons correlates with a stable nuclear higher-order structure

Neurons become terminally differentiated (TD) post-mitotic cells very early during development yet they may remain alive and functional for decades. TD neurons preserve the molecular machinery necessary for DNA synthesis that may be reactivated by different stimuli but they never complete a successf...

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Detalles Bibliográficos
Autor principal: Aranda-Anzaldo, Armando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376047/
https://www.ncbi.nlm.nih.gov/pubmed/22808316
http://dx.doi.org/10.4161/cib.18761